Compound Q&A
How is (Z)-Roxithromycin (CAS: 134931-00-3) typically synthesized?
Answer
(Z)-Roxithromycin is synthesized via a semi-synthetic route from erythromycin, with key steps involving azalide formation and modification of the macrolide ring. The synthesis typically requires catalysts such as platinum(II) tetraacetate, and yields around 70-80%. The reaction is selective and environmentally friendly.
About
CAS No
134931-00-3
English Name
(Z)-Roxithromycin
Molecular Formula
C41H76N2O15
Molecular Weight
837.06 g/mol
SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N\OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InChIKey
RXZBMPWDPOLZGW-HEWSMUCTSA-N
Last Updated: 2026-03-26 08:46
