Compound Q&A
How is (4-Bromo-2-fluorophenoxy)acetic acid (CAS: 451-90-1) typically synthesized?
Answer
(4-Bromo-2-fluorophenoxy)acetic acid is typically synthesized via a multi-step process involving bromination of 2-fluorophenol followed by esterification. Commonly, a Grignard reagent or a bromoalkane is used as the brominating agent, and acetic anhydride is employed for esterification. The yield is generally around 70-80%, and the reaction is monitored using chromatography.
About
CAS No
451-90-1
English Name
(4-Bromo-2-fluorophenoxy)acetic acid
Molecular Formula
C8H6BrFO3
Molecular Weight
249.03 g/mol
SMILES
C1=CC(=C(C=C1Br)F)OCC(=O)O
InChIKey
HPXDHKIIFGVHOU-UHFFFAOYSA-N
Last Updated: 2026-03-23 04:12
