Compound Q&A
How is N-[(2Z)-3-Benzyl-4-(hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide (CAS: 2687970-96-1) typically synthesized?
Answer
![N-[(2Z)-3-Benzyl-4-(hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide](https://static.chemtradehub.com/structs/268/2687970-96-1-7f0a.webp "N-[(2Z)-3-Benzyl-4-(hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide")
N-[(2Z)-3-Benzyl-4-(hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide can be synthesized by a multi-step process involving the condensation of an appropriate thiazole and pyrrole derivative. Typically, this involves the use of a catalyst such as a Lewis acid, and the reaction is carried out in an organic solvent. The yield is usually moderate to good, and the product can be purified by column chromatography or recrystallization.
About
CAS No
2687970-96-1
English Name
N-[(2Z)-3-Benzyl-4-(hydroxymethyl)-1,3-thiazol-2(3H)-ylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
Molecular Formula
C19H16N4O2S
Molecular Weight
364.43 g/mol
SMILES
OCC1=CS/C(=N\C(=O)C2=CNC3N=CC=CC2=3)/N1CC1C=CC=CC=1
InChIKey
LJNPGPUDPDQGLE-QOCHGBHMSA-N
Last Updated: 2026-03-22 19:38
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