Compound Q&A

How is 4-(Cyclopropylmethoxy)-2-fluorobenzoic Acid (CAS: 742086-08-4) typically synthesized?

Answer

4-(Cyclopropylmethoxy)-2-fluorobenzoic Acid
4-(Cyclopropylmethoxy)-2-fluorobenzoic Acid can be synthesized via a multi-step process involving the protection of the aromatic ring, introduction of the cyclopropylmethoxy group, and subsequent deprotection. Commonly, Grignard reagents or organometallic compounds are used as catalysts. The overall yield is moderate, around 50-70%, and selectivity is high for the desired product.

About

English Name 4-(Cyclopropylmethoxy)-2-fluorobenzoic Acid
Molecular Formula C11H11FO3
Molecular Weight 210.20399999999995 g/mol
SMILES O=C(O)C1=CC=C(OCC2CC2)C=C1F
InChIKey VKUOOCAJGLYUED-UHFFFAOYSA-N
Last Updated: 2026-03-22 19:38

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