Compound Q&A

How is 5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine (CAS: 66335-37-3) typically synthesized?

Answer

5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine
5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine is synthesized through a multi-step process that includes the introduction of a fluorine atom and isopropylidene group to the cytidine structure. Common synthetic routes involve the use of protected cytidine derivatives, followed by fluorination and isopropylidene protection steps. The yield and selectivity of these reactions are crucial for the successful production of this compound.

About

CAS No 66335-37-3
English Name 5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine
Molecular Formula C12H16FN3O4
Molecular Weight 285.28 g/mol
SMILES CC1C2C(C(O1)N3C=C(C(=NC3=O)N)F)OC(O2)(C)C
InChIKey XXYNQHIPVNHJFE-VPCXQMTMSA-N
Last Updated: 2026-03-22 14:59

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