Compound Q&A
How is Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4) typically synthesized?
Answer
Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4) is typically synthesized by the reaction of methyl glycinate with phenol in the presence of a strong acid catalyst such as hydrochloric acid. The reaction involves esterification followed by acid hydrolysis to form the hydrochloride salt. Conditions are controlled to achieve high selectivity and yield, often conducted under reflux and monitored using thin-layer chromatography (TLC).
About
CAS No
515028-39-4
English Name
Methyl N-phenylglycinate hydrochloride (1:1)
Molecular Formula
C9H12ClNO2
Molecular Weight
201.65 g/mol
SMILES
COC(=O)CNC1=CC=CC=C1.Cl
InChIKey
AJHZGVMKIXHMNP-UHFFFAOYSA-N
Last Updated: 2026-03-20 10:59
