Methyl N-phenylglycinate hydrochloride (1:1)(CAS: 515028-39-4)

Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4) is a white crystalline solid with a molecular weight of approximately 218.3 g/mol. It is slightly soluble in water and highly soluble in organic solvents such as ethanol and acetone. This compound is stable under neutral and slightly acidic conditions but may hydrolyze in strongly alkaline environments. It is not reactive with common reagents but should be handled with care to avoid strong bases.

Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4) is typically synthesized by the reaction of methyl glycinate with phenol in the presence of a strong acid catalyst such as hydrochloric acid. The reaction involves esterification followed by acid hydrolysis to form the hydrochloride salt. Conditions are controlled to achieve high selectivity and yield, often conducted under reflux and monitored using thin-layer chromatography (TLC).

Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also utilized in the production of semiconductors as a dopant and in polymer synthesis as a monomer. Additionally, it finds application in the development of sensors and as a chemical reagent in analytical chemistry.

When handling Methyl N-phenylglycinate hydrochloride (CAS: 515028-39-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, protective goggles, and a lab coat. This compound should be stored in a cool, dry place away from strong bases and acids. In case of spill, it should be cleaned up carefully using appropriate absorbent materials. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for this compound.