Compound Q&A
How is 1-(4-Methoxyphenyl)guanidine (CAS: 67453-80-9) typically synthesized?
Answer
1-(4-Methoxyphenyl)guanidine is commonly synthesized through the reaction of 4-methoxybenzylamine with carbodiimide in the presence of a base. This method provides good yield and selectivity. The reaction involves the formation of an amide linkage and the removal of a carbodiimide derivative as a byproduct.
About
CAS No
67453-80-9
English Name
1-(4-Methoxyphenyl)guanidine
Molecular Formula
C8H11N3O
Molecular Weight
165.2 g/mol
SMILES
COC1=CC=C(C=C1)N=C(N)N
InChIKey
VGFALHATLLBXIT-UHFFFAOYSA-N
Last Updated: 2026-03-20 06:42
