Compound Q&A

How is Ethyl 3,5-diiodo-L-tyrosinate hydrochloride (CAS: 74051-47-1) typically synthesized?

Answer

Ethyl 3,5-diiodo-L-tyrosinate hydrochloride (1:1)
Ethyl 3,5-diiodo-L-tyrosinate hydrochloride (CAS: 74051-47-1) is synthesized by reacting 3,5-diiodo-L-tyrosine with ethyl chloroformate in the presence of a catalyst such as pyridine. The reaction is performed under anhydrous conditions, and the product is isolated by recrystallization from ethanol. The yield is approximately 70-80%.

About

CAS No 74051-47-1
English Name Ethyl 3,5-diiodo-L-tyrosinate hydrochloride (1:1)
Molecular Formula C11H14ClI2NO3
Molecular Weight 497.5 g/mol
SMILES CCOC(=O)C(CC1=CC(=C(C(=C1)I)O)I)N.Cl
InChIKey ILBBOCVXEPIPBR-FVGYRXGTSA-N
Last Updated: 2026-03-20 06:42

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