Compound Q&A

What are the physical and chemical properties of N-(7-Chloro-1-{(3R)-1-[(2E)-4-(dimethylamino)-2-butenoyl]-3-azepanyl}-1H-benzimidazol-2-yl)-2-methylisonicotinamide methanesulfonate (CAS: 1508250-72-3)?

Answer

N-(7-Chloro-1-{(3R)-1-[(2E)-4-(dimethylamino)-2-butenoyl]-3-azepanyl}-1H-benzimidazol-2-yl)-2-methylisonicotinamide methanesulfonate (1:1)
N-(7-Chloro-1-{(3R)-1-[(2E)-4-(dimethylamino)-2-butenoyl]-3-azepanyl}-1H-benzimidazol-2-yl)-2-methylisonicotinamide methanesulfonate (CAS: 1508250-72-3) is a crystalline compound with a molecular weight of approximately 621.9 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as dimethylformamide (DMF) and acetonitrile. This compound is relatively stable under normal storage conditions but reacts with strong bases to form the amine. It exhibits high reactivity towards nucleophiles and can undergo substitution reactions at the 7-position of the benzimidazole ring.

About

English Name N-(7-Chloro-1-{(3R)-1-[(2E)-4-(dimethylamino)-2-butenoyl]-3-azepanyl}-1H-benzimidazol-2-yl)-2-methylisonicotinamide methanesulfonate (1:1)
Molecular Formula C27H35ClN6O5S
Molecular Weight 591.1340000000005 g/mol
SMILES Cc1cc(ccn1)C(=O)Nc2nc3cccc(c3n2[C@@H]4CCCCN(C4)C(=O)/C=C/CN(C)C)Cl.CS(=O)(=O)O
InChIKey BJRYTAMUVASSBY-ZJULCNDBSA-N
Last Updated: 2026-03-19 20:21

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