Compound Q&A
How is H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-NH2 (CAS: 83139-29-1) typically synthesized?
Answer
H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-NH2 (CAS: 83139-29-1) is typically synthesized via solid-phase peptide synthesis (SPPS). The process involves stepwise addition of amino acids under mild conditions using a peptide coupling reagent. The final deprotection and cleavage steps yield the desired peptide. Key parameters include the choice of coupling reagent, side-chain protection strategies, and purification methods such as HPLC.
About
CAS No
83139-29-1
English Name
H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-NH2
Molecular Formula
C181H292N56O50S2
Molecular Weight
4116.73041629791 g/mol
SMILES
S(C)CC[C@@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](CCC(=O)O)C(N[C@@H](CCCNC(=N)N)C(N[C@H](C(N[C@@H](CCC(=O)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(=O)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC1C=CC=CC=1)=O)CC(N)=O)=O)CC1=CN=CN1)=O)C(C)C)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC1=CNC2C=CC=CC1=2)=O)=O)C(C)C)=O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CC1=CN=CN1)=O)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(=O)O)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CO)N)=O)=O)=O)=O)=O)=O)=O
InChIKey
RRBCHMCWWOHRQL-UMXFMPSGSA-N
Last Updated: 2026-03-19 20:21
