Compound Q&A

How is Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0) typically synthesized?

Answer

Methyl 2-amino-3-oxobutanoate
Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0) can be synthesized by the amidation of methyl 2-oxobutanoate with ammonia. The reaction is typically catalyzed by a strong base like potassium carbonate in an aprotic solvent like dimethylformamide (DMF). The yield is usually above 85% with good regioselectivity.

About

CAS No 68277-01-0
English Name Methyl 2-amino-3-oxobutanoate
Molecular Formula C5H9NO3
Molecular Weight 131.13 g/mol
SMILES CC(=O)C(C(=O)OC)N
InChIKey JJJKPDCCZFMOJD-UHFFFAOYSA-N
Last Updated: 2026-03-17 06:03

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