Methyl 2-amino-3-oxobutanoate(CAS: 68277-01-0)

Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0) is a white crystalline solid with a molecular weight of 119.12 g/mol. It has a solubility of 1.4 g/L in water and is slightly soluble in ethanol. It is moderately reactive, particularly under basic conditions. It can undergo nucleophilic substitution and condensation reactions.

Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0) can be synthesized by the amidation of methyl 2-oxobutanoate with ammonia. The reaction is typically catalyzed by a strong base like potassium carbonate in an aprotic solvent like dimethylformamide (DMF). The yield is usually above 85% with good regioselectivity.

Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also used in the production of some polymers and as a reagent in chemical research. Its applications in sensors and semiconductors are still under development.

When handling Methyl 2-amino-3-oxobutanoate (CAS: 68277-01-0), it is recommended to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. In case of a spill, use a fume hood and follow standard spill control procedures. Always refer to the Safety Data Sheet (SDS) for detailed information.