Compound Q&A
How is 5-[(4-Chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid (CAS: 338760-78-4) typically synthesized?
Answer
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5-[(4-Chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid is typically synthesized via sulfenylation of 1,2,3-thiadiazole-4-carboxylic acid with 4-chlorophenylthiol. This reaction is usually performed in the presence of a catalytic amount of base such as potassium carbonate or sodium hydride. The yield is generally around 80%, and the product can be isolated by recrystallization from suitable solvents.
About
CAS No
338760-78-4
English Name
5-[(4-Chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid
Molecular Formula
C9H5ClN2O2S2
Molecular Weight
272.74 g/mol
SMILES
C1=CC(=CC=C1SC2=C(N=NS2)C(=O)O)Cl
InChIKey
NDYKFFAREALEPX-UHFFFAOYSA-N
Last Updated: 2026-03-17 01:51
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