Compound Q&A
How is 6-chloro-3-phenyl-pyridin-2-amine (CAS: 69214-19-3) typically synthesized?
Answer
6-Chloro-3-phenyl-pyridin-2-amine is typically synthesized via a multi-step process involving the protection of a pyridine nitrogen, followed by chlorination, and subsequent deprotection. Commonly, this involves the use of acetyl chloride for protection, N-chlorosuccinimide for chlorination, and TFA for deprotection. The overall yield is moderate, around 50-60%, depending on the purity of the intermediates.
About
CAS No
69214-19-3
English Name
6-chloro-3-phenyl-pyridin-2-amine
Molecular Formula
C11H9ClN2
Molecular Weight
204.66 g/mol
SMILES
C1=CC=C(C=C1)C2=C(N=C(C=C2)Cl)N
InChIKey
NOGZPCDWPPVALQ-UHFFFAOYSA-N
Last Updated: 2026-03-16 17:23
