Compound Q&A
How is (E)-N-(4-Amino-1-hydroxybutylidene)-L-histidine (CAS: 3650-73-5) typically synthesized?
Answer
(E)-N-(4-Amino-1-hydroxybutylidene)-L-histidine can be synthesized by a multi-step process involving the condensation of 4-amino-1-hydroxybutanone with L-histidine. The reaction typically requires a Lewis acid catalyst and proceeds with high selectivity. The yield is usually around 80-90%, and the purity can be enhanced through recrystallization.
About
CAS No
3650-73-5
English Name
(E)-N-(4-Amino-1-hydroxybutylidene)-L-histidine
Molecular Formula
C10H16N4O3
Molecular Weight
240.26 g/mol
SMILES
C1=C(NC=N1)CC(C(=O)O)NC(=O)CCCN
InChIKey
CCLQKVKJOGVQLU-QMMMGPOBSA-N
Last Updated: 2026-03-16 17:23
