Compound Q&A

How is 6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one (CAS: 72916-61-1) typically synthesized?

Answer

6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one is typically synthesized via a cyclization reaction of an appropriate chromanone intermediate with a 3-methyl-2-buten-1-yl halide. This process involves the use of a Lewis acid catalyst, such as aluminum chloride, and proceeds with good selectivity. The overall yield is around 70-80% depending on the purity of reagents and reaction conditions.

About

CAS No 72916-61-1
English Name 6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
Molecular Formula C16H18O4
Molecular Weight 274.32 g/mol
SMILES CC(=CCc1c2c(ccc(=O)o2)cc(c1OC)OC)C
InChIKey NNBURDJZOIAAHY-UHFFFAOYSA-N
Last Updated: 2026-03-16 17:23

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