6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one(CAS: 72916-61-1)

6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one is a crystalline compound with a molecular weight of approximately 304.18 g/mol. It has a low solubility in water (0.01 g/L at 25°C) and is soluble in common organic solvents like dichloromethane and ethanol. The compound is moderately reactive towards nucleophiles and is stable under basic conditions. It exhibits strong absorption in the UV/Vis region, suggesting potential use in analytical chemistry applications.

6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one is typically synthesized via a cyclization reaction of an appropriate chromanone intermediate with a 3-methyl-2-buten-1-yl halide. This process involves the use of a Lewis acid catalyst, such as aluminum chloride, and proceeds with good selectivity. The overall yield is around 70-80% depending on the purity of reagents and reaction conditions.

6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one has applications in the pharmaceutical industry for the development of anti-inflammatory and analgesic agents. It is also utilized in the polymer industry for the synthesis of advanced materials and in the chemical sensor industry for developing highly sensitive gas detectors. Additionally, it has potential in the semiconductor industry for use in organic electronics.

When handling 6,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one, it is essential to wear protective equipment such as gloves, goggles, and a lab coat. It should be stored in a dry, well-ventilated area away from oxidizing agents and moisture. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed spill management and emergency procedures. Safe handling procedures and fume hood usage are critical to prevent inhalation and skin contact.