Compound Q&A

How is 4-fluoro-3-(4-piperidinyl)-1,2-Benzisoxazole (CAS: 95742-20-4) typically synthesized?

Answer

4-fluoro-3-(4-piperidinyl)-1,2-Benzisoxazole
4-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole is typically synthesized by the condensation of 4-fluorobenzisoxazole with 4-piperidone in the presence of a catalyst such as p-toluenesulfonic acid (p-TSA). The reaction is optimized for high yield and selectivity, often exceeding 90%.

About

CAS No 95742-20-4
English Name 4-fluoro-3-(4-piperidinyl)-1,2-Benzisoxazole
Molecular Formula C12H13FN2O
Molecular Weight 220.25 g/mol
SMILES C1CNCCC1C2=NOC3=C2C(=CC=C3)F
InChIKey GVMQXMFLUSCQJS-UHFFFAOYSA-N
Last Updated: 2026-03-16 13:10

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