What regulatory guidelines apply to 2-Cyanoacrylic acid (CAS: 15802-18-3)?

2-Cyanoacrylic acid (CAS: 15802-18-3) is subject to various regulatory guidelines including the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations, and FDA/EPA requirements for its handling and use. It is classified as a toxic substance and may require specific labeling and safety data sheets (SDS) under GHS. Under REACH, manufacturers and importers must register the substance if the annual tonnage threshold is exceeded. FDA regulations may apply to the use of 2-Cyanoacrylic acid in pharmaceuticals or cosmetics, ensuring it meets purity and safety standards.