Compound Q&A
How is (6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (CAS: 144790-28-3) typically synthesized?
Answer
![(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](https://static.chemtradehub.com/structs/144/144790-28-3-ba30.webp "(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid")
This compound is synthesized through a multi-step process involving peptide coupling reactions and condensation reactions. Commonly, a protected amino acid is coupled with an appropriate linker to form the desired structure. Catalysts such as HATU or EDC are used, and the yield can typically reach up to 70-80% with high selectivity.
About
CAS No
144790-28-3
English Name
(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Formula
C16H17N3O5S
Molecular Weight
363.4 g/mol
SMILES
CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O
InChIKey
BOEGTKLJZSQCCD-FIXISWKDSA-N
Last Updated: 2026-03-10 14:55
![(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
![(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid — ShenZhenZhenJiangShengWuJiShu Co Ltd](https://static.chemtradehub.com/suppliers/67cec9142b2de6e8e95a51e7/67cec9142b2de6e8e95a51e7-logo.webp){kind=logo}
![(6R,7R)-7-{[(2S)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}