Compound Q&A
How is N-Cbz-guanidine (CAS: 16706-54-0) typically synthesized?
Answer
N-Cbz-guanidine is synthesized by the amidation of guanidine with p-chlorobenzyl chlorides. This reaction is typically catalyzed by a phase-transfer catalyst and proceeds with good yield. The product is then purified by recrystallization from appropriate solvents.
About
CAS No
16706-54-0
English Name
N-Cbz-guanidine
Molecular Formula
C9H11N3O2
Molecular Weight
193.21 g/mol
SMILES
C1=CC=C(C=C1)COC(=O)N=C(N)N
InChIKey
FZOCFRPFPKJHHP-UHFFFAOYSA-N
Last Updated: 2026-03-08 09:14
