Compound Q&A

How is (2S)-5-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-5-oxo-2-(palmitoylamino)pentanoic acid (CAS: 294855-91-7) typically synthesized?

Answer

(2S)-5-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-5-oxo-2-(palmitoylamino)pentanoic acid (non-preferred name)
The compound is synthesized through a multi-step process involving the formation of a pyrrolidone intermediate followed by alkylation and amidation reactions. Commonly, the intermediate is treated with a palmitoyl chloride in the presence of a base such as triethylamine. The reaction conditions and catalysts used can vary, but the goal is to achieve a high yield and good selectivity towards the desired product.

About

English Name (2S)-5-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-5-oxo-2-(palmitoylamino)pentanoic acid (non-preferred name)
Molecular Formula C25H42N2O7
Molecular Weight 482.61800000000034 g/mol
SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)ON1C(=O)CCC1=O)C(O)=O
InChIKey KLBZDGJNRTVIAJ-FQEVSTJZSA-N
Last Updated: 2026-03-08 09:14

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