Compound Q&A

How is 1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, hydrobromide, (S)- (CAS: 75776-79-3) typically synthesized?

Answer

1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylicacid, hydrobromide, (S)- (9CI)
1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, hydrobromide, (S)- is typically synthesized through a multi-step process involving the condensation of 1,4-dithiane and 1,4-diazaspiro[4.4]nonane, followed by bromination. The reaction is catalyzed by a Lewis acid such as aluminum chloride, and the product is isolated and purified by recrystallization. The overall yield is around 70%.

About

CAS No 75776-79-3
English Name 1,4-Dithia-7-azaspiro[4.4]nonane-8-carboxylicacid, hydrobromide, (S)- (9CI)
Molecular Formula C7H12BrNO2S2
Molecular Weight 286.2 g/mol
SMILES C1CSC2(S1)CC(NC2)C(=O)O.Br
InChIKey DXALUCGGSBGKIY-JEDNCBNOSA-N
Last Updated: 2026-03-08 09:14

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