Compound Q&A
How is Biotin-PEG2-C4-alkyne (CAS: 1011268-28-2) typically synthesized?
Answer
Biotin-PEG2-C4-alkyne (CAS: 1011268-28-2) is synthesized by linking a biotin moiety to a polyethylene glycol (PEG) chain through a C4 alkynyl group. Commonly, biotin is attached to the PEG chain via an amide bond. The synthesis typically involves coupling biotin hydrazide with the carboxylic acid of the C4 alkynyl-PEG2 derivative. This process can be optimized using specific coupling agents and conditions to achieve high yields and selectivity.
About
CAS No
1011268-28-2
English Name
Biotin-PEG2-C4-alkyne
Molecular Formula
C22H36N4O5S
Molecular Weight
16.043 g/mol
SMILES
C#CCCCC(=O)NCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@H]2[C@@H]1NC(=O)N2
InChIKey
VNWKTOKETHGBQD-UHFFFAOYSA-N
Last Updated: 2026-03-08 04:51