Compound Q&A
How is 4-[4-(2-Pyrimidinyl)-1-piperazinyl]-1-butanamine (CAS: 33386-20-8) typically synthesized?
Answer
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4-[4-(2-Pyrimidinyl)-1-piperazinyl]-1-butanamine (CAS: 33386-20-8) is typically synthesized through a multi-step reaction involving the coupling of 2-pyrimidinyl bromide with 4-(2-pyrimidinyl)piperazine followed by reaction with 1-butanamine. The reaction is catalyzed by a phase-transfer catalyst and proceeds with high selectivity and yield, often higher than 90%.
About
CAS No
33386-20-8
English Name
4-[4-(2-Pyrimidinyl)-1-piperazinyl]-1-butanamine
Molecular Formula
C12H21N5
Molecular Weight
235.34 g/mol
SMILES
C1CN(CCN1CCCCN)C2=NC=CC=N2
InChIKey
YDQAUSHJSHIVAD-UHFFFAOYSA-N
Last Updated: 2026-03-08 04:51
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