Compound Q&A

How is 2,5-Dioxo-3-pyrrolidinecarboxylic acid (CAS: 96905-69-0) typically synthesized?

Answer

2,5-Dioxo-3-pyrrolidinecarboxylic acid
2,5-Dioxo-3-pyrrolidinecarboxylic acid can be synthesized through the dehydrative condensation of pyrrolidinecarboxylic acid with phosgene. Alternatively, it can be prepared by the condensation of 1,5-dioxepan-2-one with glycine. The synthesis typically involves the use of a dehydrating agent and a mild base, with high yields and good selectivity.

About

CAS No 96905-69-0
English Name 2,5-Dioxo-3-pyrrolidinecarboxylic acid
Molecular Formula C5H5NO4
Molecular Weight 143.1 g/mol
SMILES C1C(C(=O)NC1=O)C(=O)O
InChIKey AZPXZTOCIRKBSJ-UHFFFAOYSA-N
Last Updated: 2026-03-08 00:27

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