Compound Q&A
How is 4-{[(Benzyloxy)carbonyl]amino}benzoic acid (CAS: 5330-71-2) typically synthesized?
Answer
![4-{[(Benzyloxy)carbonyl]amino}benzoic acid](https://static.chemtradehub.com/structs/533/5330-71-2-ab1a.webp "4-{[(Benzyloxy)carbonyl]amino}benzoic acid")
4-{[(Benzyloxy)carbonyl]amino}benzoic acid can be synthesized via the coupling of benzyloxycarbonyl chloride with aniline followed by condensation with benzoic acid. The reaction is typically performed in an organic solvent such as dichloromethane or acetonitrile with a suitable base like triethylamine. The yield is generally around 85-90%.
About
CAS No
5330-71-2
English Name
4-{[(Benzyloxy)carbonyl]amino}benzoic acid
Molecular Formula
C15H13NO4
Molecular Weight
271.27 g/mol
SMILES
C1=CC=C(C=C1)COC(=O)NC2=CC=C(C=C2)C(=O)O
InChIKey
XRKLFEVNZWRMCT-UHFFFAOYSA-N
Last Updated: 2026-03-07 19:49
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