Compound Q&A
How is 5-(2-Methylphenyl)-1,3,4-oxadiazole-2(3H)-thione (CAS: 2503-66-4) typically synthesized?
Answer
5-(2-Methylphenyl)-1,3,4-oxadiazole-2(3H)-thione is typically synthesized via the condensation of 2-methylphenyl isothiocyanate with oxalic acid dihydrazide. The reaction proceeds at room temperature with good yield and selectivity. The use of a mild base such as pyridine can enhance the reaction efficiency and product purity.
About
CAS No
2503-66-4
English Name
5-(2-Methylphenyl)-1,3,4-oxadiazole-2(3H)-thione
Molecular Formula
C9H8N2OS
Molecular Weight
192.24 g/mol
SMILES
CC1=CC=CC=C1C2=NNC(=S)O2
InChIKey
HNFIJWNVPWXSOL-UHFFFAOYSA-N
Last Updated: 2026-03-07 19:49
