Compound Q&A
How is 2-(4-Nitrophenyl)propanenitrile (CAS: 50712-63-5) typically synthesized?
Answer
2-(4-Nitrophenyl)propanenitrile (CAS: 50712-63-5) is commonly synthesized through the reaction of 2-chloropropanenitrile with 4-nitrophenoxyboronic acid in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium(0). This method provides high yield and selectivity. Other routes involve the nitration of 2-phenylpropanenitrile followed by hydrogenation.
About
CAS No
50712-63-5
English Name
2-(4-Nitrophenyl)propanenitrile
Molecular Formula
C9H8N2O2
Molecular Weight
176.17 g/mol
SMILES
CC(C#N)C1=CC=C(C=C1)[N+](=O)[O-]
InChIKey
QCPKTMACPAKCKW-UHFFFAOYSA-N
Last Updated: 2026-03-07 15:41
