Compound Q&A

How is Chlormadinone (CAS: 1961-77-9) typically synthesized?

Answer

Chlormadinone
Chlormadinone (CAS: 1961-77-9) is typically synthesized through a multi-step process involving the reduction of 17α-methyl-17β-chlorocorticosterone. The reaction proceeds through the use of lithium aluminum hydride (LAH) as a reducing agent, followed by further chemical modifications such as acetylation and methylation, with high selectivity and moderate yield.

About

CAS No 1961-77-9
English Name Chlormadinone
Molecular Formula C21H27ClO3
Molecular Weight 362.9 g/mol
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)CCC34C)Cl)C)O
InChIKey VUHJZBBCZGVNDZ-TTYLFXKOSA-N
Last Updated: 2026-03-05 12:33

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