Compound Q&A

How is 3-Oxo-4-isoindolinecarbaldehyde (CAS: 771-08-4) typically synthesized?

Answer

3-Oxo-4-isoindolinecarbaldehyde
3-Oxo-4-isoindolinecarbaldehyde is typically synthesized through the condensation of 4-isoindoline-1,3-dione with formaldehyde using an acid catalyst, such as hydrochloric acid or sulfuric acid. The reaction is carried out under reflux conditions, and the product is isolated by recrystallization from an appropriate solvent. The yield of the reaction is typically around 75-85%, with good selectivity to the desired product.

About

CAS No 771-08-4
English Name 3-Oxo-4-isoindolinecarbaldehyde
Molecular Formula C9H7NO2
Molecular Weight 161.16 g/mol
SMILES C1C2=C(C(=CC=C2)C=O)C(=O)N1
InChIKey IUZIMWDWXWFSKZ-UHFFFAOYSA-N
Last Updated: 2026-03-05 12:33

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