Compound Q&A

How is 3,5-Dibromo-1H-indole (CAS: 81387-89-5) typically synthesized?

Answer

3,5-Dibromo-1H-indole
3,5-Dibromo-1H-indole is typically synthesized through the bromination of indole using bromine and a Lewis acid catalyst, such as aluminum trichloride. The reaction involves the electrophilic aromatic substitution of indole with bromine, leading to the formation of the dibromo derivative with good yield and selectivity.

About

CAS No 81387-89-5
English Name 3,5-Dibromo-1H-indole
Molecular Formula C8H5Br2N
Molecular Weight 274.94 g/mol
SMILES C1=CC2=C(C=C1Br)C(=CN2)Br
InChIKey NGTBILHUFBABDS-UHFFFAOYSA-N
Last Updated: 2026-03-05 06:57

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