Compound Q&A
How is 5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide (CAS: 1350653-27-8) typically synthesized?
Answer
![5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide](https://static.chemtradehub.com/structs/135/1350653-27-8-47b6.webp "5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide")
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide can be synthesized through a multi-step process involving alkylation and nucleophilic aromatic substitution reactions. Typically, this involves the reaction of 2-fluorobenzyl bromide with a 5-fluoropyrazolo[3,4-b]pyridine derivative. The synthesis usually requires the use of a phase-transfer catalyst and occurs with high selectivity, yielding a product with a purity of over 95%.
About
CAS No
1350653-27-8
English Name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide
Molecular Formula
C14H11F2N5
Molecular Weight
287.27 g/mol
SMILES
NC(=N)C1=NN(CC2=CC=CC=C2F)C2=NC=C(F)C=C21
InChIKey
QHNLOUKOONWPRR-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11
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