Compound Q&A
How is 4,6-Dichloro-2-(3-pyridinyl)pyrimidine (CAS: 89508-47-4) typically synthesized?
Answer
4,6-Dichloro-2-(3-pyridinyl)pyrimidine is typically synthesized through the condensation of 2-aminopyrimidine with 3-chloropyridine in the presence of a base like sodium hydride. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) under anhydrous conditions. The process yields a highly selective product with good purity and yield.
About
CAS No
89508-47-4
English Name
4,6-Dichloro-2-(3-pyridinyl)pyrimidine
Molecular Formula
C9H5Cl2N3
Molecular Weight
226.07 g/mol
SMILES
C1=CC(=CN=C1)C2=NC(=CC(=N2)Cl)Cl
InChIKey
RECDDDYREDDCDJ-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11
