Compound Q&A

How is 2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione (CAS: 106981-52-6) typically synthesized?

Answer

2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione
2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione is synthesized through a multi-step process, involving the protection of the amino group, coupling with an appropriate partner, and subsequent deprotection. Commonly, this involves using amines and isoindoline-1,3-dione derivatives, catalyzed by palladium or rhodium complexes, leading to high selectivity and good yields.

About

English Name 2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione
Molecular Formula C16H14N2O3
Molecular Weight 282.3 g/mol
SMILES CCOC1=C(C=CC(=C1)N)N2C(=O)C3=CC=CC=C3C2=O
InChIKey CWFMBSOEQIOZAR-UHFFFAOYSA-N
Last Updated: 2026-03-05 02:11

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