2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione(CAS: 106981-52-6)

2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione is a crystalline compound with a molecular weight of approximately 314.37 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophilic substitution and can undergo coupling reactions under certain conditions. Its solubility and reactivity make it useful in various chemical syntheses.

2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione is synthesized through a multi-step process, involving the protection of the amino group, coupling with an appropriate partner, and subsequent deprotection. Commonly, this involves using amines and isoindoline-1,3-dione derivatives, catalyzed by palladium or rhodium complexes, leading to high selectivity and good yields.

2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione is used in pharmaceuticals for developing new drugs, in polymer science for synthesizing functional materials, and in sensor technology for detecting specific chemical species. Its reactivity and specific functional groups make it valuable in these industries.

When handling 2-(4-Amino-2-ethoxyphenyl)isoindoline-1,3-dione, ensure the use of proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place, away from direct sunlight and flammable materials. Always use a fume hood for handling to minimize inhalation risks. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.