Compound Q&A

How is 2'-Deoxy-5-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]uridine (CAS: 86163-17-9) typically synthesized?

Answer

2'-Deoxy-5-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]uridine
2'-Deoxy-5-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]uridine is typically synthesized via a multistep route involving the protection of the nucleoside, introduction of the methoxy group, and subsequent ring opening and closure steps. This process requires the use of specific catalysts and reagents to ensure high selectivity and yield, with careful control of reaction conditions to prevent side reactions.

About

CAS No 86163-17-9
English Name 2'-Deoxy-5-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]uridine
Molecular Formula C13H16N2O7
Molecular Weight 312.28 g/mol
SMILES COC(=O)/C=C/c1cn(c(=O)[nH]c1=O)[C@H]2C[C@@H]([C@H](O2)CO)O
InChIKey RKTRMSPWWLPPAY-YJCWOPNRSA-N
Last Updated: 2026-03-05 02:11

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