How is Ethyl 4-amino-6-chloro-5-iodonicotinate (CAS: 1935952-84-3) typically synthesized?

Ethyl 4-amino-6-chloro-5-iodonicotinate is synthesized through a multi-step process involving condensation reactions and halogenation. It typically requires the use of catalysts such as N,N'-carbonyldiimidazole (CDI) for the amidation step and iodine for the halogenation step. The overall reaction involves the introduction of an amino group and subsequent halogenation, leading to the desired compound.