Compound Q&A

How is Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate (CAS: 56649-47-9) typically synthesized?

Answer

Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate is typically synthesized through a multi-step process involving the reaction of ethyl chloroacetate with 1-(1-phenylethyl)-1H-imidazole in the presence of a base such as potassium carbonate. The product is then isolated and purified by recrystallization from a suitable solvent. This method provides good yield and selectivity.

About

CAS No 56649-47-9
English Name Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
Molecular Formula C14H16N2O2
Molecular Weight 244.29 g/mol
SMILES CCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2
InChIKey NPUKDXXFDDZOKR-UHFFFAOYSA-N
Last Updated: 2026-03-01 18:39

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