Compound Q&A
How is (5alpha,5'alpha)-2-Bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman (CAS: 65700-36-9) typically synthesized?
Answer
The compound is typically synthesized through a multistep process involving bromination of a precursor, followed by the introduction of a hydroxyl group, isobutyl and isopropyl groups. The synthesis involves the use of reagents such as NBS (N-bromosuccinimide) and catalytic amounts of selenium dioxide. The process yields a selective product with good purity, though the exact yield varies depending on the conditions.
About
CAS No
65700-36-9
English Name
(5alpha,5'alpha)-2-Bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman
Molecular Formula
C32H40BrN5O5
Molecular Weight
654.61 g/mol
SMILES
CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@@H]4CN([C@@H]5Cc6c7c(cccc7[nH]c6Br)C5=C4)C)O
InChIKey
OZVBMTJYIDMWIL-SHUSXKRSSA-N
Last Updated: 2026-01-13 10:36
