Compound Q&A

How is delta23-FK-506 (CAS: 104987-16-8) typically synthesized?

Answer

delta23-FK-506
Delta23-FK-506 is typically synthesized through a multi-step process involving protection of functional groups, selective deprotection, and ring formation. Common methods include use of Lewis acids as catalysts and involve a series of reactions such as alkylation, acylation, and intramolecular cyclization. The overall yield is around 30-40%, with careful control of reaction conditions ensuring high selectivity.

About

English Name delta23-FK-506
Molecular Formula C44H67NO11
Molecular Weight 786.02 g/mol
SMILES CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C=CC(=O)C(C=C(C1)C)CC=C)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC
InChIKey PLHJNIVKYISEQW-ADGUVUBISA-N
Last Updated: 2026-01-13 10:36

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