Compound Q&A
How is 3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid (CAS: 22871-58-5) typically synthesized?
Answer
![3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid](https://static.chemtradehub.com/structs/228/22871-58-5-86b7.webp "3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid")
3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid is typically synthesized by reacting 2-hydroxyethyl isocyanate with 2,4,6-triiodobenzoic acid in the presence of a base like sodium hydroxide. The reaction is conducted under careful temperature control to ensure high selectivity and yield. The product is then purified by recrystallization or column chromatography.
About
CAS No
22871-58-5
English Name
3-Amino-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
Molecular Formula
C10H9I3N2O4
Molecular Weight
601.9 g/mol
SMILES
C(CO)NC(=O)C1=C(C(=C(C(=C1I)N)I)C(=O)O)I
InChIKey
WGLWRCXOMJLZME-UHFFFAOYSA-N
Last Updated: 2026-01-13 10:35
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