Compound Q&A
What is Aprotinin (CAS: 9004-04-0)?
Answer
Aprotinin is a protein isolate derived from the pancreas of cattle. It is a serine protease inhibitor with a molecular weight of approximately 43 kDa. Aprotinin is known for its ability to inhibit various proteases, including trypsin, plasmin, and kallikrein. It is used in clinical settings to reduce blood loss and the need for transfusion during surgery.
About
CAS No
9004-04-0
English Name
APROTININ
Molecular Formula
C284H432N84O79S7
Molecular Weight
6511.44 g/mol
EINECS
232-994-9
SMILES
[H]/N=C(/N)NCCC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)NCC(=O)NCC(=O)N[C@H](C)C(=O)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](CCCN/C(N)=N/[H])NC(=O)[C@H](CCSC)NC(=O)[C@H]2CSSC[C@H]3NC(=O)[C@@H](CC(C)C)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H](Cc4ccc(O)cc4)NC(=O)[C@@H](CCCN/C(N)=N\[H])NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCN/C(N)=N/[H])NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CSSC[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@@H](C(C)C)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC3=O)C(=O)N[C@@H](CCCN/C(N)=N/[H])C(=O)N[C@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN/C(N)=N\[H])C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N2)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@@H]([C@H](C)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](CC(C)C)NC1=O
InChIKey
ZPNFWUPYTFPOJU-YSFZTAPISA-N
Last Updated: 2026-01-09 14:49
