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APROTININ(CAS: 9004-04-0)
CAS Number
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Other Suppliers for APROTININ
Basic Information
Molecular Formula
C284H432N84O79S7
Molecular Weight
6511.44 g/mol
EINECS
232-994-9
Physical State
white
Chemical Identifiers
SMILES
[H]/N=C(/N)NCCC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CSSC[C@@H](C(=O)NCC(=O)NCC(=O)N[C@H](C)C(=O)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](CCCN/C(N)=N/[H])NC(=O)[C@H](CCSC)NC(=O)[C@H]2CSSC[C@H]3NC(=O)[C@@H](CC(C)C)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc4ccc(O)cc4)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H](Cc4ccc(O)cc4)NC(=O)[C@@H](CCCN/C(N)=N\[H])NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCN/C(N)=N/[H])NC(=O)[C@@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CSSC[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@@H](C(C)C)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC3=O)C(=O)N[C@@H](CCCN/C(N)=N/[H])C(=O)N[C@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN/C(N)=N\[H])C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](Cc3ccccc3)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N2)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@@H]([C@H](C)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](CC(C)C)NC1=O
InChIKey
ZPNFWUPYTFPOJU-YSFZTAPISA-N
FAQ
Aprotinin is a protein isolate derived from the pancreas of cattle. It is a serine protease inhibitor with a molecular weight of approximately 43 kDa. Aprotinin is known for its ability to inhibit various proteases, including trypsin, plasmin, and kallikrein. It is used in clinical settings to reduce blood loss and the need for transfusion during surgery.
Aprotinin is primarily used as an antifibrinolytic agent to reduce blood loss during surgery, particularly in cardiac, orthopedic, and neurosurgical procedures. It is also used to decrease the need for blood transfusions and to treat acute blood loss. However, its use has been limited due to concerns about potential adverse effects such as kidney and lung complications.
Aprotinin is generally considered safe when used as directed. However, it has been associated with serious adverse effects including acute renal failure, pulmonary complications, and allergic reactions. It is important to follow medical guidelines and use appropriate preventive measures to minimize risks. Close monitoring is necessary during administration.
Aprotinin should be stored in a tightly closed container to protect it from light and moisture. It is best stored at a temperature between 2°C and 8°C (36°F to 46°F). Avoid freezing and excessive heat. The product should be kept out of reach of children and away from direct sunlight. Ensure the container is airtight to maintain its stability and efficacy.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
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