Compound Q&A
How is 7-Amino-4-(trifluoromethyl)-2(1H)-quinolinone (CAS: 58721-76-9) typically synthesized?
Answer
7-Amino-4-(trifluoromethyl)-2(1H)-quinolinone is synthesized via the condensation of 4-chloroquinoline-2(1H)-one with trifluoroacetic anhydride. The reaction is carried out in a mixture of acetic acid and trifluoroacetic anhydride, with a yield of about 70-80%. The reaction is catalyzed by a suitable acid and is typically conducted under mild conditions.
About
CAS No
58721-76-9
English Name
7-Amino-4-(trifluoromethyl)-2(1H)-quinolinone
Molecular Formula
C10H7F3N2O
Molecular Weight
228.17 g/mol
SMILES
C1=CC2=C(C=C1N)NC(=O)C=C2C(F)(F)F
InChIKey
JBCMJMNWLFZJNV-UHFFFAOYSA-N
Last Updated: 2026-01-07 10:17
