Compound Q&A

How is 2-(4-Fluorophenyl)-1,3-oxazole (CAS: 885268-39-3) typically synthesized?

Answer

2-(4-Fluorophenyl)-1,3-oxazole
2-(4-Fluorophenyl)-1,3-oxazole can be synthesized via a multistep process, often starting with 4-fluorophenyl isothiocyanate and then reacting it with an appropriate aldehyde or ketone in the presence of a base. Common methods include the Wittig reaction or the Pinnick oxidation. The yield is generally around 65-80%, and the reaction is highly selective, making it an efficient route for the compound's synthesis.

About

English Name 2-(4-Fluorophenyl)-1,3-oxazole
Molecular Formula C9H6FNO
Molecular Weight 163.15 g/mol
SMILES C1=CC(=CC=C1C2=NC=CO2)F
InChIKey VIWONCNRYPUJLL-UHFFFAOYSA-N
Last Updated: 2026-01-07 05:52

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