Compound Q&A

How is 5-Bromo-N-(pyridin-4-YL)pyrimidin-2-amine (CAS: 887433-72-9) typically synthesized?

Answer

5-Bromo-N-(pyridin-4-YL)pyrimidin-2-amine
5-Bromo-N-(pyridin-4-YL)pyrimidin-2-amine is typically synthesized through a multi-step process involving bromination of a pyrimidine derivative followed by nucleophilic aromatic substitution with pyridine. The reaction is often catalyzed by Lewis acids and requires careful control of reaction conditions to achieve high selectivity and yield.

About

English Name 5-Bromo-N-(pyridin-4-YL)pyrimidin-2-amine
Molecular Formula C9H7BrN4
Molecular Weight 251.08700000000002 g/mol
SMILES C1=CN=CC=C1NC2=NC=C(C=N2)Br
InChIKey NWQAMMQNVDCGEY-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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