Compound Q&A
How is 3,5-Difluoro-2-pyridinecarbaldehyde (CAS: 780801-58-3) typically synthesized?
Answer
3,5-Difluoro-2-pyridinecarbaldehyde (CAS: 780801-58-3) can be synthesized via the reaction of 2,4,6-trifluoropyridine with phosgene followed by hydrolysis. Alternatively, it can be prepared from 3,5-difluoropyridine through a condensation reaction with acetaldehyde, using a suitable catalyst such as a Lewis acid or other organometallic reagents. The yield and selectivity can be influenced by reaction conditions and the choice of catalyst.
About
CAS No
780801-58-3
English Name
3,5-Difluoro-2-pyridinecarbaldehyde
Molecular Formula
C6H3F2NO
Molecular Weight
143.09 g/mol
SMILES
C1=C(C=NC(=C1F)C=O)F
InChIKey
LNBLQSIETHAQMW-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
