Compound Q&A
How is Mometasone Furoate Monohydrate (CAS: 141646-00-6) typically synthesized?
Answer
Mometasone furoate monohydrate is synthesized by the furoylation of mometasone acetate. This involves reacting mometasone acetate with furoic anhydride in the presence of a catalyst such as p-toluenesulfonic acid. The yield is typically around 80%, and the process requires careful control of temperature and reaction time to ensure selectivity and purity.
About
CAS No
141646-00-6
English Name
Mometasone Furoate Monohydrate
Molecular Formula
C27H32Cl2O7
Molecular Weight
539.45 g/mol
SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C.O
InChIKey
AQCCVUHZMIMSIB-HRVPQZBTSA-N
Last Updated: 2026-01-04 19:14
